I've always been desperate to see a Fullmetal Alchemist/Anita Blake Crossover, Edward and Anita in a room together hehehe! Both lost their mum's, she would treat him like a kid, he would get pissy, ah the drama!!
(I have actually got a whole plotline sorted out for Edward in Anita's world fic but have yet to write it, le sigh) I could so see Edward and Asher together though, after all both their bodies have been deemed ugly and they have lost almost everything important to themselves, if that's not something to bond over I don't know what is.